I'm not sure why you brought up immunocompromised people. Does that have anything to do with the video you linked? Seems like a wash, they are immunocompromised and anything they catch will have time to live and mutate in them, not just covid19. Maybe this is something separate we should set aside? Or I don't understand the relevance.
I watched enough of the video you sent to see what Dr. Bosche was saying - that vaccination immunity is more specific than natural immunity, and that may present problems down the road with variants. I also found this note/presentation/slides by him [0]. I read some of this to get more detail, video is kind of lame for relating so much information. I'm not a virologist. But I have read a bunch of this stuff. I thought what Dr. Bosche said was interesting. I had a few initial questions. I'd love to see more virologist's opinions on this.
He says "Covid-19, a highly mutable virus, only needs to add another few mutations in its receptor-binding domain". I didn't know that covid19 was considered highly mutable, like the flu. Is he hedging here, saying this might happen? I guess the specific proteins that the vaccines target would need to mutate. I wonder how likely this is. I assume there are lots of things that are "several mutations" away from killing us all. Papers I've seen early on said that left to its own covid19 had a 50/50 chance of mutating to become no more deaadly than the common cold (because it would spread better that way), or settle into something that flares up every few years, like a bad flu season. I took that to mean that there are also pressures to mutate to something less deadly. They think this is what may have happened in 1873 (if memory serves), a new coronavirus came on the scene, it looked like a very bad flu season at the time.
He mentioned several cases of young people dying from covid19 variants, and several cases of people shedding variants. "Several" is not a large number, especially considering how much we don't understand about the immune system. Typhoid Mary was shedding for years, and that had nothing to do with a vaccine. I don't know that I'd consider his several examples to be anything out of the ordinary out of a sample size of how many tens of millions.
He seems to be saying we'd be better off if we didn't proceed with vaccinations and allowed the population to reach natural herd immunity at this point, since covid19 has already spread to so many people. That people who caught it and got better on their own would be better protected. This reminds me of the virologist early on who recommended finding the least deadly variant and spreading that around on purpose.
It's an interesting topic, and I appreciate you bringing it up! I don't mean to argue over it, so much as relay my thoughts and left some of the details of what he's saying.
Do you think most of the people fearful of variants are on the same page with this guy? The news stories I see mentioning problems with vaccines and variants don't ever seem to have solid sources/studies backing them up, I've never heard this guy mentioned before, and he seems to be a relatively lone voice at this point. I'd like to think that the experts have had a chance to hash all this out amongst themselves, but I know things don't always work out that nicely.
I watched enough of the video you sent to see what Dr. Bosche was saying - that vaccination immunity is more specific than natural immunity, and that may present problems down the road with variants. I also found this note/presentation/slides by him [0]. I read some of this to get more detail, video is kind of lame for relating so much information. I'm not a virologist. But I have read a bunch of this stuff. I thought what Dr. Bosche said was interesting. I had a few initial questions. I'd love to see more virologist's opinions on this.
He says "Covid-19, a highly mutable virus, only needs to add another few mutations in its receptor-binding domain". I didn't know that covid19 was considered highly mutable, like the flu. Is he hedging here, saying this might happen? I guess the specific proteins that the vaccines target would need to mutate. I wonder how likely this is. I assume there are lots of things that are "several mutations" away from killing us all. Papers I've seen early on said that left to its own covid19 had a 50/50 chance of mutating to become no more deaadly than the common cold (because it would spread better that way), or settle into something that flares up every few years, like a bad flu season. I took that to mean that there are also pressures to mutate to something less deadly. They think this is what may have happened in 1873 (if memory serves), a new coronavirus came on the scene, it looked like a very bad flu season at the time.
He mentioned several cases of young people dying from covid19 variants, and several cases of people shedding variants. "Several" is not a large number, especially considering how much we don't understand about the immune system. Typhoid Mary was shedding for years, and that had nothing to do with a vaccine. I don't know that I'd consider his several examples to be anything out of the ordinary out of a sample size of how many tens of millions.
He seems to be saying we'd be better off if we didn't proceed with vaccinations and allowed the population to reach natural herd immunity at this point, since covid19 has already spread to so many people. That people who caught it and got better on their own would be better protected. This reminds me of the virologist early on who recommended finding the least deadly variant and spreading that around on purpose.
It's an interesting topic, and I appreciate you bringing it up! I don't mean to argue over it, so much as relay my thoughts and left some of the details of what he's saying.
Do you think most of the people fearful of variants are on the same page with this guy? The news stories I see mentioning problems with vaccines and variants don't ever seem to have solid sources/studies backing them up, I've never heard this guy mentioned before, and he seems to be a relatively lone voice at this point. I'd like to think that the experts have had a chance to hash all this out amongst themselves, but I know things don't always work out that nicely.
[0] https://www.deblauwetijger.com/wp-content/uploads/2021/03/Ge...