I have a close friend who has chronic fatigue. It is commonly stigmatized as many regard those who are chronically fatigued as lazy, just making excuses.

But my friend is one of the hardest-working, most productive people I have met and is quite wealthy as a result at first of her code, then as a result of her management expertise.

Even so she feels like crap 24/7 and it just won't go away. Nothing helps.

She can be a little hard to get along with, though.