Some of my favourites (in no particular order):

1. NPR Planet Money -- http://www.npr.org/blogs/money/

2. Talking Machines -- http://www.thetalkingmachines.com/

3. Intelligence squared (debates; through NPR) -- http://www.npr.org/series/6263392/intelligence-squared-u-s/

I've also heard good things about Marketplace -- http://www.marketplace.org/podcasts