I wish he had acknowledged the role of good luck. Clearly, he worked hard to get where he is, but how many other comics have done the same?

(I don't know much about the comedy business, though...maybe there just aren't many people who put in as much time as Louis C.K.)

Luck gives opportunity, nonstop hard work is what keeps you from squandering it. Successful comedians (even the terribly unfunny ones) just don't quit. Plenty of people get where they are through luck, but I don't think comedy is the sort of field where people just "fall into" their careers.

There are plenty of funny comedians who don't make it big (Eddie Pepitone comes to mind) and work hard, but you can't describe how to get lucky, all you can describe is how to not fuck up opportunity.