Psychopy is a mess of a project. It hasn't gotten any better from my perspective, even after hiring full time developers, because most of their effort is focused on the single-gui-app and Pavolovia.
I'm afraid uv can't do anything about that, nor could any other packaging tool. (Except perhaps one custom-made by the developers, but just getting on board with standards and best practices would surely be easier.)
things did get better when they added wheels.