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That's like reading the announcement of new software and saying, get back to us when they discover all the bugs.

Naturally, there will be adverse events due to toxicity. But unless you have some particular insight into why this should be much worse in this case than for other drugs, merely mentioning that there will be toxicities doesn't really advance the discussion. At least, not as written.



Do you realize that only 9% of drugs pass from Phase I of clinical trials to the FDA approval?

Do you know why? Because the "cure" is worse than what they are supposed to treat.


Likewise, a small fraction of startups become successful.

Also, your allegation is wrong. Generally the reason for failure is not adverse events, but lack of efficacy/effectiveness.

Will this likely fail? Yes. Will it likely fail due to adverse events? No. Will it likely fail due to inefficacy/ineffectiveness? Yes.




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