His district is comprised of rural areas and wealthier parts of Austin/SA in a republican state, so that seems highly unlikely unless he somehow alienates his base and faces a strong republican challenger.
It's an interesting test. Reddit / "the internet" would have to find a candidate who could win in that district that they could support.
It would involve some serious value judgments and compromises (a liberal dem is not going to get elected there), and my bet would be that they simply are not capable of it in the end.
I'm not making that assumption, but perhaps I am assuming/implying that this issue isn't enough on the radar of most republicans to have much of an impact in a primary race. And as noted by waterlesscloud, a democrat can't win this district.