> Case fatality rates were noted in three studies at 0.000002%, 0.00009%, and 0.0001%.
Fatal allergic reactions are so rare as to be completely irrelevant as a cause of death. Most of them are drug induced and most of those occur in hospitals when someone has an allergic reaction to an intravenous drug, not something they eat [2]. They're unlikely to be a significant driver of any evolutionary adaptation.
> Case fatality rates were noted in three studies at 0.000002%, 0.00009%, and 0.0001%.
Fatal allergic reactions are so rare as to be completely irrelevant as a cause of death. Most of them are drug induced and most of those occur in hospitals when someone has an allergic reaction to an intravenous drug, not something they eat [2]. They're unlikely to be a significant driver of any evolutionary adaptation.
[1] https://onlinelibrary.wiley.com/doi/epdf/10.1111/all.12272
[2] https://linkinghub.elsevier.com/retrieve/pii/S00916749140119...