If venvs were a reasonable solution here, presumably the pyspread authors would have included them in the installation instructions. Instead they just say to "pip install", which predictably does not work for most people. It sounds a bit unfair to tell someone that "they're the problem" when they followed the official installation instructions to the letter. I would agree in classifying this as another case of python developers being unable to provide a working way to install their software (if code that the average person can't even get to execute can even be called "software".)