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Your assessment is more or less spot on. We are replacing many pipetting steps with electric and magnetic manipulation of samples on a surface.

Traditionally these operations when done manually (or even on other automation) are done inside tubes. When these operations are carried out inside tubes you have many limitations: you end up using a lot of tips, when pipetting manually some workflows require special techniques to pipette handle the samples. These operations are also extremely painful when do them over and over again -- very tedious and very easy to make a mistake.

Yes we have seen increase in throughputs relative to human. Most humans (often) process samples in batches of 8 / 12 samples. To give you a sense of the length of the workflow in a lab it can range from two hours to two days. The Callisto system can process anywhere from 1 - 24 samples for many workflows and is software controlled. It not only eliminates the manual steps: it provides at least 3X the throughput with 15 mins setup time, provides reproducible results and improves quality.



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