Plenty of FDA-approved drugs have nasty side effects. Isotretinoin will cause such massive birth defects that usually a doctor will get a female user to sign an agreement that she won't get pregnant while taking it.
It has a number of other significant side effects - for me, marked loss of physical strength, plus delicate skin susceptible to sunburn while taking it. But the 6-month course was worth it - cleared up my facial acne to an incredible degree. I had simply gotten used to the fact that my face was always in pain. Now I still get the odd pimple (like most people), but nothing like the boils I used to get.
It has a number of other significant side effects - for me, marked loss of physical strength, plus delicate skin susceptible to sunburn while taking it. But the 6-month course was worth it - cleared up my facial acne to an incredible degree. I had simply gotten used to the fact that my face was always in pain. Now I still get the odd pimple (like most people), but nothing like the boils I used to get.