There's quite a bit of interest; e.g. ex-colleagues of mine have spent lots of effort on refining the 'chemoton' model. I think it's a fascinating subject.
"The basic assumption of the model is that life should fundamentally and essentially have three properties: metabolism, self-replication, and a bilipid membrane.[3] The metabolic and replication functions together form an autocatalytic subsystem necessary for the basic functions of life, and a membrane encloses this subsystem to separate it from the surrounding environment. Therefore, any system having such properties may be regarded as alive, and it will be subjected to natural selection and contain a self-sustaining cellular information."
"The basic assumption of the model is that life should fundamentally and essentially have three properties: metabolism, self-replication, and a bilipid membrane.[3] The metabolic and replication functions together form an autocatalytic subsystem necessary for the basic functions of life, and a membrane encloses this subsystem to separate it from the surrounding environment. Therefore, any system having such properties may be regarded as alive, and it will be subjected to natural selection and contain a self-sustaining cellular information."
https://en.wikipedia.org/wiki/Chemoton
https://www.nationalgeographic.com/premium/article/he-may-ha...