Nobody actually does this commute 5 days a week, 45-50 weeks a year. It's either someone who does it sporadically but regularly (e.g. every other Monday or something for a few years) or briefly while finding something less insane (for a few weeks, maybe a month or two).
I had a job with an effective ~4-hour round trip commute, from one major city to another in both my car and a train, but only had to do it once a month.
I used to have a similar commute into NYC. I lived about a 10 minute walk from the train station and my office was another 10 minute walk from Grand Central Station. Round trip was about 4 hours. I did the commute about 3 days per week but saw tons of people on the train that did it every day. I saw a guy talking to the conductor saying it was his last time commuting after THIRTY YEARS. I imagine most of those people were driving to the train station and then taking another subway once they made it into the city, adding a considerable amount of time to the already brutal commute.
I take the 510 AM train from Albany to NYC about once a month. There’s a dozen folks who are on that train enough that I recognize them or chat with them. There’s a few who board at Hudson too.
It’s a mix of lawyers, construction guys and others like FDNY guys.
If I go into the city for a customer visit (not frequent/not rare), I'm 2 hours going in whether mostly train or mostly car. And about the same going home by train and maybe more like an hour+ by car.
I did have a job that was about 90 minutes door-to-door each way (train schedules were a bit better then) but even then "only" had to do it about 50% of the time. Wouldn't have been long-term sustainable.
I had a job with an effective ~4-hour round trip commute, from one major city to another in both my car and a train, but only had to do it once a month.