Possibly, as an absolute last resort. Not before. It's very unlikely, and at that point it being "more effective" than ketamine is barely germane, since I'm scraping the bottom of the barrel anyway.
But that's what treatment-resistant depression is: either a life in misery, suicide or ECT/Ket as a hail-Mary maneuver. We are not talking about acute depression or people in midlife-crisis.
