That's a severe misunderstanding of how these compounds work
On one hand you have a single acute dose (in your words "jolting") which can profoundly 'rewire' synaptic connections
On the other hand you have a compound administered chronically to induce changes that may not last after removing the medication. The goal is the same rewiring but considering dropout rates and success rates of treatment its absolutely lacklustre
Generally speaking, the compounds that are illegal are more profoundly impactful because if their high affinity and specificity than compounds available for prescription
On one hand you have a single acute dose (in your words "jolting") which can profoundly 'rewire' synaptic connections
On the other hand you have a compound administered chronically to induce changes that may not last after removing the medication. The goal is the same rewiring but considering dropout rates and success rates of treatment its absolutely lacklustre
Generally speaking, the compounds that are illegal are more profoundly impactful because if their high affinity and specificity than compounds available for prescription