It depends. My nodeRed flow for grabbing various sensor data and sending them to influxdb: https://pictshare.net/mvarpf.png

And my home alarm system flow: https://pictshare.net/82qfpa.png

To be fair though you can create sub-flows to have it more compact but when I designed it, I didn't know about theseyet

I use node-red for the same kind of things, with subflows. At some point it makes a lot more sense to write a function node (javascript) than to use node-red as intended. Avoids a lot of the spaghetti.

I suppose so, but perhaps trying to prevent the spaghettification has some positive benefits in terms of DRY + code structure.

No.