Well, this study passes the "we dumped a bunch of X on cancer cells in a petri dish and they did a funny thing" red flag test.
Xenographs (implanting human cancer cells into mice) have their own caveats (the immune system is almost always severely compromised), but this seems like a cool study. I'm no expert on oral cancers however.
Curious to see the implication of the neuronal cells here, I'm looking forward to reading the whole manuscript.
Cancer cells can consume multiple energy sources, not exactly news here. Concluding that dietary palmitic acid is a problem is questionable. Palmitate is produced endogenously and dietary palmitic acid does not even influence tissue concentration [1].
> Palmitate is produced endogenously and dietary palmitic acid does not even influence tissue concentration [1].
If there's no uptake by tissue, then wouldn't the tumor have a plentiful energy source once it vascularizes? (Assuming they can metabolize palmitic acid)
Xenographs (implanting human cancer cells into mice) have their own caveats (the immune system is almost always severely compromised), but this seems like a cool study. I'm no expert on oral cancers however.
Curious to see the implication of the neuronal cells here, I'm looking forward to reading the whole manuscript.