This doesn't make any sense......gaming hardware for office work sucks and I used to be an avid gamer. Gaming chairs are garbage. Gaming keyboards do not have much ergonomics in mind, there are much better and comfortable options from logitech and microsoft but they don't light up like a Christmas tree. Gaming mice have many buttons and DPI switches and logitech mx master is much more comfortable than any gaming mouse I used over the years.
If you want to be comfortable you need to research and be willing to drop $1000+ on a chair and peripherals.
Funny enough, I've never gotten on with ergonomic mice/keyboards. Switching from Logitech to mechanical some years ago made wrist pain go away and it never came back.
I agree that many buttons (which appears to be mostly mice intended for MOBAs or MMORPGs) is not good. My current desktop mouse is a Corsair Glaive (https://www.corsair.com/us/en/glaive-rgb-gaming-mouse) which has a very normal button set.
If you want to be comfortable you need to research and be willing to drop $1000+ on a chair and peripherals.