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But you have to be careful about that word "independent".

There's a reason that things like 3D protein structure estimation, for example, are still very difficult problems, because none of the coordinates are even approximately independent of the others.

So you're back to a standard "minimization is really difficult" even in ultra-high dimensional spaces.



Yeah I was thinking about that as I was writing and trying to convey why I feel like deep models are different. I think one way of thinking about it is that protein structure, even though it has lots of parameters, it is all happening within the confines of 3D space. A protein that could move in lots of dimensions at once, could probably reliably fold much more easily, and it would be easy to find this structure.




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