I've only had to update it two times to fix bugs with android upgrades,so all in all not too bad.
Google did once randomly pulled my app without warning (just an email after they pulled it) for violating some terms, without stating what terms.
I couldnt get any useful feedback, eventually I just bumped the version number and rewrote the description, that got met back on the store. But it did make me very weary of building anything their platform.