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I'm not sure there is anything else with the flexibility of D/RNA. Its self-replicating property is fundamental. Is there something else known to work anything like this?


Some possible alternatives are covered here: https://en.wikipedia.org/wiki/Nucleic_acid_analogue

And I agree that RNA and DNA are pretty good molecules and probably close to some notion of 'optimal'. The ribosome, however, is big and complicated and there are probably millions of different ways something like that could have come about and that would affect the 3-base codon, protein structures, etc.

Also, look at the contortions DNA has to go through to copy what's called the "lagging strand". Clearly duplicating double-stranded DNA did not come early or easily; it's pretty obvious a system bolted on top of some other, older system. https://en.wikipedia.org/wiki/DNA_replication#Lagging_strand




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