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It's not just antibiotics, but some types of vaccines are creating evolutionary pressure and new strains of the pathogen. E.g. for pertussis

> it is thought that B. pertussis is adapting under acellular vaccine mediated immune selection pressure, towards vaccine escape [1]

> an increase in asymptomatic infection with concomitant increases in transmission and increased selection pressure for Bordetellapertussis variants that are better able to evade vaccine-mediated immunity than older isolates [2]

[1] https://academic.oup.com/femspd/article/73/8/ftv064/2467598

[2] https://www.sciencedirect.com/science/article/pii/S156713481...



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