It's worth pointing out, you don't need to go through all the menus. Most (all?) functionality accessible in menus can be put on a button on the status bar. I have my Enable JavaScript checkbox down at the bottom, next to disabling images and CSS (useful for SEO work).
While we're pointing out different ways to disable JS, the F12-menu is also nice to have. F12 pops up a menu with some handy settings, including "Enable plugins" and "Enable JavaScript".
