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..."Indyke, an attorney who represented Epstein for decades, has not been criminally indicted by federal authorities. He was hired by the Parlatore Law Group in 2022, before the justice department settled the Epstein case. That firm represents the defense secretary, Pete Hegseth, and previously represented Donald Trump in his defense against charges stemming from the discovery of classified government documents stored at Trump’s Florida estate."...

From the Guardian UK https://archive.md/lO08a


Projectivy Launcher, for Nvidia Shield Home Screen. Before that I was building a rooted firmware and downgrading from that awful advert ridden update. I also tried Dispatch as a home screen replacement, but Projectivy wins.

Not a book, but a 'fact'book; https://www.cia.gov/the-world-factbook/countries/iran/

Religions

Muslim (official) 98.5%, Christian 0.7%, Baha'i 0.3%, agnostic 0.3%, other (includes Zoroastrian, Jewish, Hindu) 0.2% (2020 est.)

Compared to the United Kingdom; https://www.cia.gov/the-world-factbook/countries/united-king...

Religions

Christian (includes Anglican, Roman Catholic, Presbyterian, Methodist) 59.5%, Muslim 4.4%, Hindu 1.3%, other 2%, unspecified 7.2%, none 25.7% (2011 est.)



First they came for the Communists And I did not speak out Because I was not a Communist Then they came for the Socialists And I did not speak out Because I was not a Socialist Then they came for the trade unionists And I did not speak out Because I was not a trade unionist Then they came for the Jews And I did not speak out Because I was not a Jew Then they came for me And there was no one left To speak out for me

Pastor Niemöller


What happened to curl? The comment is referring to how the curl project is being overwhelmed by low-quality bug/vulnerability reports generated (or partially generated) by AI (“AI slop”), so much so that curl maintainers are now banning reporters who submit such reports and demanding disclosure, because these sloppy reports cost a lot of time and drain the team.

[generated by ChatGPT] Source: https://news.ycombinator.com/item?id=45217858


Yes, https://www.thisamericanlife.org/505/use-only-as-directed

The episode shows how even small overdoses of acetaminophen can cause fatal liver damage, while decades of FDA delays and confusing drug labeling left millions of Americans at risk.


Tylenol is very safe if taken as prescribed. The overdose amount is relatively low, but not uniquely low.

The alternatives are worse - ibuprofen destroys your stomach lining if taken at the regular dose for too long.


Ibuprofen also increases risk of strokes and NSAIDs have been linked to increased risk of intracerebral hemorrhage. It’s a question of whether benefits outweigh cons on population level and I am not an expert, but recommending ibuprofen over acetaminophen might be over-simplifying things. It depends on the person (their meds, their pre-existing conditions, their genetics etc)


"Tylenol is very safe if taken as prescribed. The overdose amount is relatively low, but not uniquely low."

The issue is that the overdose of Paracetamol is relatively similar to the effective, or safe, dose:

"(overdose) of paracetamol is caused by taking more than the recommended maximum daily dose of paracetamol for healthy adults (three or four grams),[38] and can cause potentially fatal liver damage. A single dose should not exceed 1000 mg ..." [1]

See the problem ? A mere 3x the single dose puts one in "potentially fatal liver damage" territory.

This problem is compounded dramatically in small children where errors in the estimation of the child's weight can put you half way to overdose before you even start. Now add a meniscus error as you fill a clear plastic cup in the middle of the night ... or Mom gives a dose at 5am without knowing that Dad already gave a dose at 2am ... ugh.

Compare this to Aspirin where the overdose is as high as 15-30x the effective dose.

[1] https://en.wikipedia.org/wiki/Paracetamol#Overdose


> Tylenol is very safe if taken as prescribed

I’ll note that if you aren’t used to taking Tylenol, be mindful of the difference between extra and regular strength. My dentist just wrote down a number of Tylenols to take every X hours, and I took them, but because they were extra strength I started hallucinating and chugging water during, I think, Detective Pikachu or some nonsense like it. My liver came out of it fine. But if I’d taken another handful poison control said they would have directed me to the ER. One more after that and it would have been permanent liver damage.


> ibuprofen destroys your stomach lining if taken at the regular dose for too long.

This is how the VA killed my dad :/


ibuprofen and similar are also much more likely to destroy your kidneys as well and exacerbate heart disease. Intermittent regular dose use is unlikely to cause kidney harm but people get in trouble in two ways: chronic extended use of higher “therapeutic” doses (800mg for ibuprofen) or they have other medical problems weakening kidney function.


Can someone explain what is being said here in literal terms please. Can you also identify any dark humour or social commentary because I don't know enough to be sure.


Let me try again:

1. People do not stay on GLP1s for long, despite how effective they are

2. People often rebound harder from other forms of weight loss (dieting, temporary lifestyle changes, etc)

3. GLP1 reduces a LOT of health risks linked to obesity (heart disease being the most important IMO)

4. Older people are taking GLP1s in droves

5. Once these drugs are everywhere (they will be soon IMO in < 7 years obesity will probably be ~gone), the effects will get "priced in" to actuary tables.

No social commentary or dark humor intended -- GLP1s aren't miracle drugs but the effects (and relative lack of side effects) is miraculous.


"It is surmised that conditioning is enforced via several cogni- tive biases that trick a player into expecting euphoria (liking- pathway), when instead frustration is yielded – with condi- tioning being iterated to a point that the player is motivated to interact with the game on a foremost instinctual level. We posit that these stimulations of the wanting-pathway may lead to players interacting with the game not only with- out actually liking it, but also without knowing why they are interacting with the game. Indeed, this calls for drawing another parallel between drug addiction, and play behaviour in which liking may be barely exhibited (cf. [16, 38, 40])."



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