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Also loo up hypothalamic microinflammation by Cai


How about yoga?


Is yoga approximately the same? What of physical therapy?


as an obsessive observer of his over the past decade, I've been concerned... It could be a product of his increased concern over public media coverage in general (he keeps his really interesting views just to himself, as Nick Cammarata mentions on Twitter), and this trend may have only intensified recently, as he has been strangely quiet


The IPO has likely been taking up a lot of time. Also, there is a blackout period before most IPOs where those in the company are not allowed to talk about the company or 'sell' it. The SEC guidelines are pretty strict and jeopardizing XYZ% of the IPO can result in millions on the gambling table.


Actually someone I know who knows Minsky says that Minsky wasn't really sharp towards his later years [that said, he still mentored students, and the Nectome cofounder was one of his last students]..


What are some microsensors that can be used to detect concentration of a protein or molecule that can then be used to make a "decision"? E.g. aggregated proteins or concentration of a particular mRNA or 4-HNE or lipofuscin accumulation?


Do people still have to specify position of {fluid 1 in well 2}=>requiring a dependence on the well or does it allow for complete position independence?


No, complete position independence is allowed and encouraged. People can put constraints on well location, like “use this plate”, but general allocation is handled by the compiler. If a well needs to be bearable, for example, that is allocated into a well that satisfies the temperature constraints of the heating operation.


What are some concrete synthetic biology workflows whose labor costs have been reduced by this?

Why do you advertise this as "being for biologists" and also "for downloading drugs" at the same time? Biologists do much much more than just synthesize drugs.

How does the program "execute" a decision once, say, it detects that the percent molar composition of molecule A exceeds that of molecule B?


Some concrete workflows are easy things like aliquotting and PCR, and as complex as PACE, a protocol for directed evolution.

The "for biologists" and "downloading drugs" only account for a small part of what we do. We use those phrases to get the point across, but you're totally right, they do a lot of stuff that we can automate such as parameter sweeps over a protocol to empirically increase the yield of the reaction.

We use normal conditionals, so if you can write an if statement with the desired branches, we can execute that. Both paths are statically allocated, currently there is only limited support for deferred routing. It's something i'm working on!


Is living near a major roadway (e.g. http://www.sciencemag.org/news/2017/01/brain-pollution-evide... ) also sufficient to cause unhealthy air?

>> Deepening the concerns, this month researchers at the University of Toronto in Canada reported in The Lancet that among 6.6 million people in the province of Ontario, those living within 50 meters of a major road—where levels of fine pollutants are often 10 times higher than just 150 meters away—were 12% more likely to develop dementia than people living more than 200 meters away.

>> Just how the fine airborne particles might travel from a rodent’s nasal cavity to its brain is a mystery. But a research team led by Günter Oberdörster at the University of Rochester in New York has used traceable, radioactive specks of elemental carbon to demonstrate that inhaled particles smaller than 200 nanometers can get through the delicate tissues lining a rodent’s nasal cavities, travel along neurons, and spread as far as the cerebellum, at the back of the brain, triggering an inflammatory reaction.

>>"In 1403 elderly women, the total volume of white matter—the insulated nerve fibers that connect different brain regions—decreased by about 6 cubic centimeters for every 3.5-µg/m3 increase in estimated PM2.5 exposure, based on air monitoring data from participants’ residences for 6 to 7 years before the brain scans were taken. Chen’s white matter findings are consistent with studies of cultured neurons, which show that exposure to PM2.5 can cause myelin—the fatty insulation that wraps around neuronal axons—to “peel up at the ends, like a Band-Aid,” Block says"

I mean, hell, even trees do increase the amount of certain types of "pollutants" in the air (pollen for one). They make the air less pure for one thing.


Unlike magnetic nanoparticles, pollen isn’t going to literally stick in your brain, just provoke an allergic reaction in some.


trees still produce air impurities beyond just pollen :)


Lol this reminds me of the Demolition Ship Captain incident at AoKH where DSC hacked into Angel THS's account (and then ban half the active users on Age of Kings Heaven) by just creating a website where he could get Angel THS to use the same password he could use everywhere (HUNTER)


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